Multidimensional Motor Evoked Potentials (MultiMEP): Digging up buried information from single trials
This proof-of-principle study demonstrates that MEPs encode richer information than previously assumed both at single-subject and at single-trial levels. Our results suggest that MultiMEP decoding represents a first step toward a paradigm shift in studying motor processes with TMS, much like multivoxel pattern analysis revolutionized the way the brain-cognition relationship has been studied through neuroimaging.
Authors
- Corrado Sinigaglia (ORCID: https://orcid.org/0000-0002-3365-7522)
- Martina Fanghella (ORCID: https://orcid.org/0000-0003-1222-2762)
- Francesco Negro (ORCID: https://orcid.org/0000-0002-9094-8932)
- Elena Mussini (ORCID: https://orcid.org/0000-0002-0900-1283)
- Marta Bortoletto (ORCID: https://orcid.org/0000-0002-8489-8043)
- Paolo Rota (ORCID: https://orcid.org/0000-0003-0663-5659)
- Agnese Zazio (ORCID: https://orcid.org/0000-0002-1395-9005)
- Luigi Cattaneo (ORCID: https://orcid.org/0000-0001-8905-7529)
- Guido Barchiesi (ORCID: https://orcid.org/0000-0002-8936-4171)
- Francesca Genovese (ORCID: https://orcid.org/0009-0000-4956-0461)
- Fabio Beltrami
Institutions
- IMT School for Advanced Studies Lucca (IT)
- University of Milan (IT)
- University of Trento (IT)
- Centro San Giovanni di Dio Fatebenefratelli (IT)
- Center for Neuroscience and Cognitive Systems (IT)
- University of Brescia (IT)
Publication Details
- Journal
- Brain stimulation
- Published
- 2025-09-04
- DOI
- https://doi.org/10.1016/j.brs.2025.09.001
- Primary Topic
- EEG and Brain-Computer Interfaces
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Università degli Studi di Milano
- Dipartimenti di Eccellenza
- Ministero della Salute
- Ministero dell’Istruzione, dell’Università e della Ricerca