Pharmaceutical Co-crystal of Ketoconazole-adipic Acid: Excipient Compatibility and In Silico Antifungal Potential Studies
The excipient compatibility study conducted on the Ketoconazole-Adipic Acid co-crystal confirmed its potential for development as a solid oral dosage form with improved antifungal activity, presenting a promising alternative to the parent drug.
Authors
- Irina Kacsó (ORCID: https://orcid.org/0000-0003-1039-0543)
- I. Grosu (ORCID: https://orcid.org/0000-0003-1174-2790)
- Flavia Martin (ORCID: https://orcid.org/0000-0002-1987-9735)
- Monica Dan (ORCID: https://orcid.org/0000-0003-1678-229X)
- Maria Olimpia Miclaus (ORCID: https://orcid.org/0000-0002-9738-2417)
- Ana Maria Raluca Gherman (ORCID: https://orcid.org/0000-0002-5250-2534)
- Xenia Filip (ORCID: https://orcid.org/0000-0001-6441-3793)
Institutions
- National Institute for Research and Development of Isotopic and Molecular Technologies (RO)
Publication Details
- Journal
- Pharmaceutical Research
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1007/s11095-025-03910-7
- Citations
- 2
- Primary Topic
- Crystallization and Solubility Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.04
Funders
- Ministerio de Economía y Competitividad
- Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii
- Ministry of Education and Research, Romania