Prognostic Significance of Liquid Biopsy-Detected Genetic Alterations in Hepatocellular Carcinoma
Liquid biopsy-detected genetic alterations correlate with clinical outcomes in HCC, underscoring the prognostic value of ctDNA analysis. Mutations in FGFR1 and FGFR3 were associated with aggressive disease, suggesting these pathways as potential therapeutic targets. Integrating liquid biopsy with other diagnostic modalities may enhance personalized management and improve prognosis for patients with HCC.
Authors
- Atılgan Tolga Akçam (ORCID: https://orcid.org/0000-0001-7525-3107)
- Harun Ağca (ORCID: https://orcid.org/0000-0002-2651-2034)
- Burak Yavuz (ORCID: https://orcid.org/0000-0002-5262-0346)
- İshak Aydın (ORCID: https://orcid.org/0000-0002-6366-2461)
- Atıl Bişgin (ORCID: https://orcid.org/0000-0002-2053-9076)
- Ahmet Gökhan Sarıtaş (ORCID: https://orcid.org/0000-0003-2715-6390)
- Abdullah Ülkü (ORCID: https://orcid.org/0000-0001-5180-1543)
- Uğur Topal (ORCID: https://orcid.org/0000-0003-1305-2056)
- Tuğsan Ballı
Institutions
- Cukurova University (TR)
Publication Details
- Journal
- Journal of Hepatocellular Carcinoma
- Published
- 2025-09-01
- DOI
- https://doi.org/10.2147/jhc.s529189
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00