Transpulmonary bubble transit in patients hospitalised with COVID-19 pneumonia
The prevalence of TPBT in hospitalised patients with COVID-19 pneumonia is higher than expected and the presence of TPBT increases over time in those that remained alive and hospitalised. In patients with TPBT, increased heart rate, a marker of hyperdynamic circulation, is associated with increased mortality.
Authors
- Alexandra S. Reynolds (ORCID: https://orcid.org/0000-0002-6364-6250)
- Hooman Poor (ORCID: https://orcid.org/0000-0001-7621-7757)
- Paul B. Yu (ORCID: https://orcid.org/0000-0003-2145-4944)
- Grayson L. Baird (ORCID: https://orcid.org/0000-0002-5926-9886)
- Kevin Rurak (ORCID: https://orcid.org/0000-0002-4496-9839)
- Corey E. Ventetuolo (ORCID: https://orcid.org/0000-0002-4223-4775)
- Maya Cohen
- Kaitlin J. Reilly-Kit
- Lillian R. Worst
- Elizabeth Shin
- Alison Lee (ORCID: https://orcid.org/0000-0001-5518-5442)
- Daniel Howell (ORCID: https://orcid.org/0000-0002-7083-0136)
- Alio Abassi (ORCID: https://orcid.org/0000-0001-7887-243X)
Institutions
- Harvard University (US)
- Brown University (US)
- National Jewish Health (US)
- Massachusetts General Hospital (US)
- Hackensack Meridian Health (US)
- New York University (US)
- University of Colorado Denver (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- BMJ Open Respiratory Research
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1136/bmjresp-2024-002912
- Primary Topic
- Respiratory Support and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- American Heart Association
- Francis Family Foundation
- National Institutes of Health