[Epidemiology, clinical characteristics and prevention strategies of Chikungunya fever].
Over the past two decades, Chikungunya virus (CHIKV), primarily transmitted by aedes-borne, has caused recurrent large-scale outbreaks across Africa, South/Southeast Asia, and Indian Ocean islands. The disease manifests with acute febrile illness, debilitating polyarthralgia, and chronic joint complications, posing significant public health burdens. Originally endemic to tropical zones, Chikungunya fever's pandemic potential has escalated due to the global expansion of aedes albopictus habitats and increased international travel. At present, 119 countries and regions around the world have reported local transmission, including recent local outbreaks in China's Guangdong Province. This review synthesizes critical insights into CHIKV's evolutionary adaptations, epidemiological characteristics, Chikungunya fever's clinical manifestations, and advances in prevention strategies and measures, aiming to inform evidence-based prevention and control measures.
Authors
- B Wang (ORCID: https://orcid.org/0009-0008-6995-3260)
- Heng Du (ORCID: https://orcid.org/0009-0006-1950-9650)
- L M Li (ORCID: https://orcid.org/0000-0002-4483-1290)
- Chunxiao Liao (ORCID: https://orcid.org/0000-0002-0336-5908)
- J Lyu (ORCID: https://orcid.org/0009-0002-6754-4371)
Institutions
- Peking University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-08-10
- DOI
- https://doi.org/10.3760/cma.j.cn112338-20250726-00527
- Primary Topic
- Mosquito-borne diseases and control
- Type
- article
- Field-Weighted Citation Impact
- 0.00