SFXN2 contributes mitochondrial dysfunction-induced apoptosis as a substrate of Parkin
Our findings offer new insights into the regulation of SFXN2 in mitochondrial dysfunction through Parkin mediated ubiquitin proteasome system activity, underscoring SFXN2's potential implications in nerodegenerative diseases, particularly PD.
Authors
- Yun He (ORCID: https://orcid.org/0000-0001-7263-3243)
- Danling Wang (ORCID: https://orcid.org/0000-0001-5933-1080)
- Shishi Luo (ORCID: https://orcid.org/0009-0005-4112-3714)
- Yaohui He (ORCID: https://orcid.org/0000-0002-8235-8924)
Institutions
- Sun Yat-sen University (CN)
- Sixth Affiliated Hospital of Sun Yat-sen University (CN)
- Changsha University of Science and Technology (CN)
- University of South China (CN)
Publication Details
- Journal
- Frontiers in Cellular Neuroscience
- Published
- 2025-08-14
- DOI
- https://doi.org/10.3389/fncel.2025.1623747
- Citations
- 1
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 1.35