Retinoic acid receptor-related orphan receptor α regulates bystander activation of memory CD8+ T cells
This study revealed a regulatory mechanism of bystander activation. The findings also improve our understanding of how memory T cells increase their immediate protective capacity through repeated infections and vaccinations.
Authors
- Kensuke Takada (ORCID: https://orcid.org/0000-0001-8999-001X)
- Kazuhiro Matsuo (ORCID: https://orcid.org/0000-0002-2329-887X)
- Hiroto Takeuchi
- Hironobu Mita
- Satoru Mizuno (ORCID: https://orcid.org/0000-0002-5724-620X)
- Mina Kozai
- Zimeng Cai (ORCID: https://orcid.org/0000-0003-1237-4686)
Institutions
- Hokkaido University of Science (JP)
- Sapporo University (JP)
- Hokkaido University (JP)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-08-14
- DOI
- https://doi.org/10.3389/fimmu.2025.1647746
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Agency for Medical Research and Development
- Ichiro Kanehara Foundation for the Promotion of Medical Sciences and Medical Care
- SENSHIN Medical Research Foundation
- Japan Society for the Promotion of Science