[Causal relationship between five autoimmune diseases and intervertebral disc degeneration:a bidirectional Mendelian analysis].
AS and IVDD may be risk factors for each other, and IVDD may be a potential risk factor for RA and SLE. These findings provide a basis for guiding the prevention and combined diagnosis and treatment of IVDD, AS, RA, and SLE, while the specific underlying mechanisms still require further experimental basic research.
Authors
- Boxue Zhang
- Xunlu Yin (ORCID: https://orcid.org/0000-0002-3388-4215)
- Yuwei Li (ORCID: https://orcid.org/0000-0003-1522-5643)
- Shuai Pei
- Ze-Ling Huang
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Wangjing Hospital of China Academy of Chinese Medical Sciences (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-08-25
- DOI
- https://doi.org/10.12200/j.issn.1003-0034.20240413
- Primary Topic
- Spine and Intervertebral Disc Pathology
- Type
- article