Targeting adipocyte differentiation with CRT0066101: activation of AMPK signaling in 3T3-L1 cells
These findings identify CRT as a novel modulator of adipocyte differentiation through AMPK activation and highlight its potential as a therapeutic candidate for obesity and metabolic syndrome.
Authors
- Xin Li (ORCID: https://orcid.org/0000-0002-3431-226X)
- Jie Zhao (ORCID: https://orcid.org/0000-0003-0624-1959)
- Wenyan Tang (ORCID: https://orcid.org/0000-0003-4250-9967)
- Jing Zhang (ORCID: https://orcid.org/0009-0002-2431-0313)
- Meijing Deng
- Qingjun Wu (ORCID: https://orcid.org/0000-0002-0344-5561)
- Jinque Luo (ORCID: https://orcid.org/0000-0002-2744-2867)
- Kun Xu (ORCID: https://orcid.org/0000-0001-5714-9090)
- Ling Wang (ORCID: https://orcid.org/0000-0003-4333-3158)
- Li Zhang (ORCID: https://orcid.org/0000-0003-0343-9476)
- Yuxin Shi
Institutions
- Changsha Medical University (CN)
- Hunan Normal University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-08-14
- DOI
- https://doi.org/10.3389/fphar.2025.1645587
- Citations
- 5
- Primary Topic
- Adipokines, Inflammation, and Metabolic Diseases
- Type
- article
- Field-Weighted Citation Impact
- 6.77
Funders
- Education Department of Hunan Province
- National Natural Science Foundation of China