Combination of nucleated red blood cells and inflammatory biomarkers (PCT and CRP) for predicting sepsis and septic shock in children
The inclusion of the NRBC count, combined with CRP and PCT, significantly increases the predictive efficacy of disease severity or progression, particularly indicative of septic shock, highlighting the potential of this combination for early diagnosis and management in pediatric patients.
Authors
- Tan Ji-hong
- Jie Cheng (ORCID: https://orcid.org/0000-0002-2452-6328)
- Dapeng Chen (ORCID: https://orcid.org/0000-0001-8412-581X)
- Liping Tan (ORCID: https://orcid.org/0000-0003-1804-2746)
- Hongdong Li (ORCID: https://orcid.org/0000-0002-5555-935X)
- Chunyi Wang (ORCID: https://orcid.org/0000-0003-1980-2786)
- Kaibin Pu
Institutions
- China International Science and Technology Cooperation (CN)
- Chongqing Maternal and Child Health Hospital (CN)
- Children's Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-08-14
- DOI
- https://doi.org/10.3389/fcimb.2025.1603216
- Citations
- 2
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- Natural Science Foundation of Chongqing
- Chongqing Municipal Education Commission
- Centre Scientifique et Technique du Bâtiment