Doxorubicin-induced nephrotoxicity: the protective role of a standardized ethanolic extract of Andrographis paniculata leaves

It is suggested that EEAP conferred renal protection against DOX-induced damage primarily through the attenuation of oxidative stress and inflammation, with andrographolide playing a significant role in the observed protective effects.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2025-08-14
DOI
https://doi.org/10.3389/fphar.2025.1585965
Citations
4
Primary Topic
Chemotherapy-induced cardiotoxicity and mitigation
Type
article
Field-Weighted Citation Impact
5.55

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article

Doxorubicin-induced nephrotoxicity: the protective role of a standardized ethanolic extract of Andrographis paniculata leaves

Wawaimuli Arozal, Nafrialdi Nafrialdi, Septelia Inawati Wanandi, Nurjati Chairani Siregar et al.
4 citations
Frontiers in Pharmacology
Chemotherapy-induced cardiotoxicity and mitigation
5.55
article

Doxorubicin-induced nephrotoxicity: the protective role of a standardized ethanolic extract of Andrographis paniculata leaves

Wawaimuli Arozal, Nafrialdi Nafrialdi, Septelia Inawati Wanandi, Nurjati Chairani Siregar, Syarifah Dewi, Oluebube Magnificient Eziefule, Melva Louisa, Ezekiel Makambwa
article en
4 citations

Abstract

It is suggested that EEAP conferred renal protection against DOX-induced damage primarily through the attenuation of oxidative stress and inflammation, with andrographolide playing a significant role in the observed protective effects.

Frontiers in PharmacologyVol. 16
University of Indonesia (ID)
Universitas Indonesia
Openalex Percentile: Top 4%
Chemotherapy-induced cardiotoxicity and mitigation
5.55
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