Innate Immunity Receptor TLR9 Drives Erythrocyte Cholesterol and Ferroprotin Accumulation in a Glutaminase-Independent Manner. Implications for Metabolic Associated Fatty Liver Disease
Erythrocyte TLR9 is upregulated in MAFLD patients and drives cholesterol and ferroportin-1 accumulation in a glutaminase-independent manner. Augmented erythrocyte TLR9 could participate in metabolic inflammation during MAFLD.
Authors
- D. S. Vlachos (ORCID: https://orcid.org/0000-0001-7225-2862)
- Konstantinos Anagnostopoulos
- Konstantinos Mimidis (ORCID: https://orcid.org/0000-0002-0783-226X)
- Charalampos Papadopoulos (ORCID: https://orcid.org/0000-0002-5084-6034)
- Zoi Kyriakou
- Nikolaos Politis
- Panagiotis Veniamis
- Tentes Ioannis
Institutions
- Democritus University of Thrace (GR)
Publication Details
- Journal
- MAEDICA – a Journal of Clinical Medicine
- Published
- 2025-03-15
- DOI
- https://doi.org/10.26574/maedica.2025.20.2.220
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00