Prognostic Significance of Mast Cell Count and Angiogenesis in Central Giant Cell Granulomas of the Jaws
Mast cell count and MVD might be used as prognostic markers of aggressive behavior of CGCGs at the time of initial biopsy. Our findings might postulate that therapeutic strategies against MC mediators and angiogenesis may benefit in aggressive CGCG as a non-surgical modality of treatment. With further studies, their prognostic significance and therapeutic application can be evaluated in patients suffering from aggressive CGCG.
Authors
- Monireh Halimi (ORCID: https://orcid.org/0000-0002-6276-6699)
- Maryam Kouhsoltani (ORCID: https://orcid.org/0000-0002-0786-0690)
- Maedeh Vakili Saatloo (ORCID: https://orcid.org/0000-0002-3724-7520)
- Shokoufeh Shahrabi‐Farahani
- Marzieh Parto
Institutions
- Boston University (US)
- University of Tennessee Health Science Center (US)
- Tabriz University of Medical Sciences (IR)
Publication Details
- Journal
- MAEDICA – a Journal of Clinical Medicine
- Published
- 2025-03-15
- DOI
- https://doi.org/10.26574/maedica.2025.20.2.283
- Primary Topic
- Mast cells and histamine
- Type
- article
- Field-Weighted Citation Impact
- 0.00