Difference in Exposure and Tolerability when Comparing Intratracheal Instillation with Inhaled Delivery
A plausible explanation for the observed but contrary to expected difference is that the drugs leaked from the lung into the systemic circulation already during the instillation procedure due to its invasive nature.
Authors
- Mikael Brűlls (ORCID: https://orcid.org/0000-0003-0700-4218)
- Elin Holmedal
- Ramon Hendrickx
Institutions
- AstraZeneca (Netherlands) (NL)
- AstraZeneca (Finland) (FI)
- AstraZeneca (Italy) (IT)
- AstraZeneca (Sweden) (SE)
Publication Details
- Journal
- Journal of Aerosol Medicine and Pulmonary Drug Delivery
- Published
- 2026-02-19
- DOI
- https://doi.org/10.1177/19412711251374845
- Primary Topic
- Family and Patient Care in Intensive Care Units
- Type
- article
- Field-Weighted Citation Impact
- 0.00