Gray matter abnormalities and memory impairment in left mesial temporal lobe epilepsy
This study expands our understanding of the memory profile in patients with MTLE. Neuropsychological testing showed that patients performed worse than controls across all assessed memory domains. Additionally, the study identified a distinct pattern of neuronal abnormalities and brain-behavior correlations. These findings suggest that the extent of structural brain anomalies may be linked to the severity of memory impairment in MTLE, underscoring the complex relationship between neuroanatomy and cognitive function in this population.
Authors
- Patrycja Naumczyk (ORCID: https://orcid.org/0000-0002-2063-222X)
- Maja Kopytek-Beuzen
- Przemysław Kunert (ORCID: https://orcid.org/0000-0002-0583-9505)
- Aleksandra Bala (ORCID: https://orcid.org/0000-0001-6239-7232)
- Agnieszka Olejnik (ORCID: https://orcid.org/0009-0002-4180-5270)
- Antonina Gottman-Narożna (ORCID: https://orcid.org/0009-0000-0515-8534)
- Weronika Rejner (ORCID: https://orcid.org/0009-0004-1083-6589)
- Andrzej Rysz
Institutions
- Medical University of Warsaw (PL)
- University of Gdańsk (PL)
- 1 Military Clinical Hospital with Outpatient Clinic (PL)
- University of Warsaw (PL)
Publication Details
- Journal
- Frontiers in Human Neuroscience
- Published
- 2025-08-14
- DOI
- https://doi.org/10.3389/fnhum.2025.1554091
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Uniwersytet Warszawski