[Current research and future perspectives on oropouche virus].
The oropouche virus (OROV) poses a threat to pregnant women and fetuses, potentially causing fetal neurological defects and even stillbirth, which has caused global attention. OROV is an arthropod-borne virus belonging to the <i>Orthobunyavirus genus</i> in the Bunyavirales order, primarily transmitted by arthropods and causing oropouche fever. This article reviews the etiological characteristics, epidemiological distribution, clinical symptoms, detection methods, and prevention strategies of OROV. OROV is prevalent in Central and South America, with a sharp increase in cases reported in Brazil in 2024. The virus's symptoms resemble those of several other arthropod-borne viral diseases, which can lead to misdiagnosis. Currently, there are no specific drugs or vaccines available, and treatment is mainly supportive. <i>Culicoides paraensis</i> and <i>Culex quinquefasciatus</i> are among the significant vectors of OROV. Furthermore, the article analyzes the distribution of <i>Culex quinquefasciatus</i> in China, highlights the risk of imported cases, proposes targeted prevention and control strategies, and underscores the significance of international cooperation in disease prevention and control.
Authors
- D S Chen
- X H Liu
- Na Jia (ORCID: https://orcid.org/0000-0002-1641-2603)
- Zhiying Chen (ORCID: https://orcid.org/0000-0001-8244-4796)
- Huijun Li (ORCID: https://orcid.org/0000-0002-2896-3867)
- Xin Chen (ORCID: https://orcid.org/0000-0002-5189-5647)
- Enhao Huang (ORCID: https://orcid.org/0009-0002-9111-4507)
- Pei-Jun He (ORCID: https://orcid.org/0009-0008-5267-5495)
- Yangxiao Cai
- Tian-Feng An
- Z Y Ren
Institutions
- Shenzhen International Travel Health Care Center (CN)
- Gannan Medical University (CN)
- Beijing Center for Disease Prevention and Control (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-08-10
- DOI
- https://doi.org/10.3760/cma.j.cn112338-20250104-00008
- Primary Topic
- Plant Virus Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00