Metabolic dysfunction-associated fatty liver in type 2 diabetes mellitus patient: can a systematic review of and meta-analysis of commonly used TCM-preparation shed light on their efficacy?
TCM-preparation can reduce the CAP value of T2DM combined with MAFLD and can have a good therapeutic effect on glucose-lipid metabolism level and liver function, indicating that TCM-preparation can reduce the deposition of hepatic fat, restore the function of hepatocytes, and have a positive effect on T2DM combined with MAFLD; however, due to the heterogeneity of the included literature, it needs to be further validation by high-quality trials.
Authors
- Jingsi Cao
- Jia Mi (ORCID: https://orcid.org/0000-0002-1374-9809)
- Xuechun Fan
- Cong Shen (ORCID: https://orcid.org/0000-0002-9982-176X)
- Ying Wang (ORCID: https://orcid.org/0000-0002-1407-2668)
- Yanyan Wang (ORCID: https://orcid.org/0000-0002-9888-9850)
- Qingwei Li (ORCID: https://orcid.org/0000-0002-1957-4464)
- Jingjing Shi (ORCID: https://orcid.org/0000-0001-9243-2414)
- Tingting Bao (ORCID: https://orcid.org/0000-0002-4431-9406)
- Jing Yu (ORCID: https://orcid.org/0000-0003-2234-8959)
- Jingxian Cao
- Rui-Xue Deng
Institutions
- Yanbian University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Ningxia Medical University (CN)
- Changchun University of Chinese Medicine (CN)
- Yanbian University Hospital (CN)
- Guang’anmen Hospital (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-08-14
- DOI
- https://doi.org/10.3389/fphar.2025.1578371
- Citations
- 1
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.35