Biotechnological Elucidation of Xinyin Tablet's Mechanism: SIRT1 Activation Attenuates Cardiac Fibrosis Via Suppressing Endothelial-to-Mesenchymal Transition.
These findings highlight XYT's biotechnological relevance by linking SIRT1 activation to EndMT inhibition, offering a novel therapeutic strategy for cardiac fibrosis. This study underscores the potential of integrating traditional medicine with molecular biotechnology to develop targeted therapies for cardiovascular diseases.
Authors
- Min Liu (ORCID: https://orcid.org/0000-0001-7231-4357)
- Taochun Ye (ORCID: https://orcid.org/0009-0007-3463-3542)
- Xin Shang (ORCID: https://orcid.org/0000-0001-6949-5046)
- Qingmin Chu (ORCID: https://orcid.org/0000-0002-1144-5211)
- Li Qiao (ORCID: https://orcid.org/0000-0002-6372-7157)
Institutions
- Guangzhou University of Chinese Medicine (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-04-01
- DOI
- https://doi.org/10.30498/ijb.2025.510746.4086
- Primary Topic
- Cardiac Fibrosis and Remodeling
- Type
- article
- Field-Weighted Citation Impact
- 0.00