3D Total Body Photography as a Promising Innovation for Early Skin Cancer Detection: Scoping Review

Although the VECTRA 3D TBP holds substantial promise for the early detection and monitoring of SC, its application cannot yet replace the expertise of trained clinicians. Although the lesion visualizer and dermoscopy explainable intelligence (DEXI) score offer potential enhancements, they also pose risks, including a significant increase in unnecessary excisions due to lower specificity. Expert overview is still recommended and superior, since there is not enough evidence yet that 3D TBP or AI is reliable on its own or beneficial as a support tool. Given the small samples and lack of blinded trials, further studies are needed to explore and improve the diagnostic capacities of 3D TBP and the possible integration of CNNs or other AI extensions and to examine the VECTRA 360WB compared to the usual standard of care.