[To taper or not to taper opioids - that is the question].

There is a lack of evidence for long-term opioid treatment of chronic non-cancer pain. According to European guidelines, opioids should not be used for primary chronic pains. It is important to continuously assess the benefits and harms of each opioid treatment and, if indicated, discontinue it as early as possible to prevent an adverse trajectory. Long-term opioid treatment is a clinically complex situation in which the issue of tapering (deprescribing) should be considered. Tapering is a medical intervention that entails planned support and close follow-up. Potential benefits include increased safety, reversal of side effects, and an improved overall situation. Risks include acute and protracted withdrawal symptoms (including worsening pain) and impaired mental health. Problematic use of opioids (including opioid use disorder) occurs in this population, but prescribers should avoid a stereotypical and stigmatizing attitude.

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Publication Details

Journal
PubMed
Published
2025-08-20
Primary Topic
Opioid Use Disorder Treatment
Type
article
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article

[To taper or not to taper opioids - that is the question].

Thomas F Kallman, Marcelo Rivano Fischer, Anders Håkansson, Patrik Midlöv et al.
PubMed
Opioid Use Disorder Treatment
article

[To taper or not to taper opioids - that is the question].

Thomas F Kallman, Marcelo Rivano Fischer, Anders Håkansson, Patrik Midlöv, Henrik Grelz, Emmanuel Bäckryd, Åsa Ringqvist, Paulin Andréll, Cecilia Grinsvall
article en

Abstract

There is a lack of evidence for long-term opioid treatment of chronic non-cancer pain. According to European guidelines, opioids should not be used for primary chronic pains. It is important to continuously assess the benefits and harms of each opioid treatment and, if indicated, discontinue it as early as possible to prevent an adverse trajectory. Long-term opioid treatment is a clinically complex situation in which the issue of tapering (deprescribing) should be considered. Tapering is a medical intervention that entails planned support and close follow-up. Potential benefits include increased safety, reversal of side effects, and an improved overall situation. Risks include acute and protracted withdrawal symptoms (including worsening pain) and impaired mental health. Problematic use of opioids (including opioid use disorder) occurs in this population, but prescribers should avoid a stereotypical and stigmatizing attitude.

PubMedVol. 122
Sahlgrenska University Hospital (SE), Danderyds sjukhus (SE), University Hospital of Umeå (SE), Beroendecentrum Stockholm (SE), Opća Bolnica Varaždin (HR), Vårdcentralen Teleborg (SE)
Openalex Percentile: Top 68%
Opioid Use Disorder Treatment
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