Milrinone versus dobutamine in acute myocardial infarction-related cardiogenic shock; a propensity score matched analysis
In this real-world propensity-matched cohort of AMI-CS patients, no significant difference in 30-day mortality was observed between patients treated with milrinone and dobutamine. Importantly, milrinone patients were more severely ill at baseline, indicating that the choice of inotrope may be influenced by illness severity. This comprehensive study suggests that the selection of inotrope may continue to be guided by individual patient characteristics.
Authors
- Luuk Otterspoor (ORCID: https://orcid.org/0000-0002-8510-8648)
- José P.S. Henriques (ORCID: https://orcid.org/0000-0002-8969-7929)
- Margriet Bogerd (ORCID: https://orcid.org/0009-0002-2554-6352)
- Elma Peters (ORCID: https://orcid.org/0000-0003-4851-1320)
- Marijke Timmermans (ORCID: https://orcid.org/0000-0002-2442-5770)
- Wim K. Lagrand (ORCID: https://orcid.org/0000-0003-2784-1961)
- Alexander P. J. Vlaar (ORCID: https://orcid.org/0000-0002-3453-7186)
- Sanne ten Berg
- Annemarie E. Engström (ORCID: https://orcid.org/0000-0002-8088-5552)
Institutions
- Radboud University Nijmegen (NL)
- Catharina Ziekenhuis (NL)
- Netherlands Heart Registration (NL)
- Amsterdam Neuroscience (NL)
- Amsterdam University Medical Centers (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- Clinical Research in Cardiology
- Published
- 2025-09-03
- DOI
- https://doi.org/10.1007/s00392-025-02742-0
- Citations
- 3
- Primary Topic
- Mechanical Circulatory Support Devices
- Type
- article
- Field-Weighted Citation Impact
- 2.02
Funders
- Amsterdam University Medical Centers
- Erasmus Medisch Centrum
- Universitair Medisch Centrum Utrecht
- Maastricht Universitair Medisch Centrum
- Leids Universitair Medisch Centrum
- Universitair Medisch Centrum Groningen
- Radboud Universitair Medisch Centrum