Optimization of a mucoadhesion testing protocol using a vertical force measurement system for chitosan- and pectin-based lyophilized polymer matrices and enteric-coated capsules
The developed method is reliable for evaluating mucoadhesion using mucin-containing media. Polymer composition, environmental pH, and lyophilization strongly influenced adhesive performance. The protocol offers a standardized tool for the design of mucoadhesive drug delivery systems.
Authors
- Adam Voelkel (ORCID: https://orcid.org/0000-0002-6536-8952)
- Mariusz Sandomierski (ORCID: https://orcid.org/0000-0001-8227-8062)
- Monika Zielińska (ORCID: https://orcid.org/0000-0002-8850-6270)
- Monika Rojewska (ORCID: https://orcid.org/0000-0002-8814-6711)
- Mária Zielińska
- Maja Wilczyńska
Institutions
- Poznań University of Technology (PL)
Publication Details
- Journal
- International Journal of Biological Macromolecules
- Published
- 2025-08-25
- DOI
- https://doi.org/10.1016/j.ijbiomac.2025.147145
- Citations
- 1
- Primary Topic
- Advanced Drug Delivery Systems
- Type
- article
- Field-Weighted Citation Impact
- 0.79