[Research progress on clinical characteristics and pathological mechanisms of lean metabolic-associated fatty liver disease].

The incidence rate of metabolic associated fatty liver disease (MAFLD) in our country has risen rapidly and has developed into the largest chronic liver disease with the rise of obesity and type 2 diabetes mellitus. Although obesity is closely related to the occurrence of MAFLD, there are still some MAFLD patients whose body mass index does not meet the criteria for obesity or overweight, which is referred to as lean MAFLD. With the continuous advancement of pathological mechanisms and clinical diagnosis and treatment technologies, relevant research on lean MAFLD has made certain progress. This article reviews the epidemiological status, pathological mechanisms and clinical diagnosis and treatment of lean MAFLD in detail.

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Publication Details

Journal
PubMed
Published
2025-08-20
DOI
https://doi.org/10.3760/cma.j.cn501113-20240528-00269
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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[Research progress on clinical characteristics and pathological mechanisms of lean metabolic-associated fatty liver disease].

Na He, Zexin Wang, Fenna Zhang, X Y Zhang et al.
PubMed
Liver Disease Diagnosis and Treatment
article

[Research progress on clinical characteristics and pathological mechanisms of lean metabolic-associated fatty liver disease].

Na He, Zexin Wang, Fenna Zhang, X Y Zhang, Boyang Lyu, S Hao
article en

Abstract

The incidence rate of metabolic associated fatty liver disease (MAFLD) in our country has risen rapidly and has developed into the largest chronic liver disease with the rise of obesity and type 2 diabetes mellitus. Although obesity is closely related to the occurrence of MAFLD, there are still some MAFLD patients whose body mass index does not meet the criteria for obesity or overweight, which is referred to as lean MAFLD. With the continuous advancement of pathological mechanisms and clinical diagnosis and treatment technologies, relevant research on lean MAFLD has made certain progress. This article reviews the epidemiological status, pathological mechanisms and clinical diagnosis and treatment of lean MAFLD in detail.

PubMedVol. 33(8)
Xi'an Medical University (CN)
Openalex Percentile: Top 68%
Liver Disease Diagnosis and Treatment
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