[Research progress on clinical characteristics and pathological mechanisms of lean metabolic-associated fatty liver disease].
The incidence rate of metabolic associated fatty liver disease (MAFLD) in our country has risen rapidly and has developed into the largest chronic liver disease with the rise of obesity and type 2 diabetes mellitus. Although obesity is closely related to the occurrence of MAFLD, there are still some MAFLD patients whose body mass index does not meet the criteria for obesity or overweight, which is referred to as lean MAFLD. With the continuous advancement of pathological mechanisms and clinical diagnosis and treatment technologies, relevant research on lean MAFLD has made certain progress. This article reviews the epidemiological status, pathological mechanisms and clinical diagnosis and treatment of lean MAFLD in detail.
Authors
- Na He (ORCID: https://orcid.org/0000-0002-5312-7510)
- Zexin Wang (ORCID: https://orcid.org/0009-0004-8534-4909)
- Fenna Zhang
- X Y Zhang (ORCID: https://orcid.org/0009-0001-7252-5186)
- Boyang Lyu (ORCID: https://orcid.org/0000-0003-3295-0652)
- S Hao
Institutions
- Xi'an Medical University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-08-20
- DOI
- https://doi.org/10.3760/cma.j.cn501113-20240528-00269
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00