Field cancerization in women without conventional risk factors: insights from a case-cohort study

This study highlights the relevance of FC in elderly OSCC patients with no history of traditional carcinogenic exposures, except for the high prevalence of denture use, which, however, cannot be considered a clear causal factor. Long-term clinical and radiological surveillance is essential for early detection of multifocal lesions, thereby improving prognosis and patient quality of life.

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Publication Details

Journal
Frontiers in Oral Health
Published
2025-08-14
DOI
https://doi.org/10.3389/froh.2025.1653210
Primary Topic
Women's cancer prevention and management
Type
article
Field-Weighted Citation Impact
0.00

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article

Field cancerization in women without conventional risk factors: insights from a case-cohort study

Nicola Mauceri, Rodolfo Mauceri, Vito Rodolico, Martina Coppini et al.
Frontiers in Oral Health
Women's cancer prevention and management
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Field cancerization in women without conventional risk factors: insights from a case-cohort study

Nicola Mauceri, Rodolfo Mauceri, Vito Rodolico, Martina Coppini, Olga Di Fede, Giuseppina Campisi, Valeria Cancila, Gaetano La Mantia, Giuseppe Seminara
article en

Abstract

This study highlights the relevance of FC in elderly OSCC patients with no history of traditional carcinogenic exposures, except for the high prevalence of denture use, which, however, cannot be considered a clear causal factor. Long-term clinical and radiological surveillance is essential for early detection of multifocal lesions, thereby improving prognosis and patient quality of life.

Frontiers in Oral HealthVol. 6
University of Messina (IT), University of Palermo (IT)
Ministero della Salute
Openalex Percentile: Top 68%
Women's cancer prevention and management
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Field cancerization in women without conventional risk factors: insights from a case-cohort study — Nicola Mauceri, Rodolfo Mauceri, et al. · Frontiers in Oral Health (2025) | TGRS Research Map | TGRS