Spiradenocylindroma: Morphology of a Rare Hybrid Adnexal Tumor

Spiradenocylindroma is a rare benign adnexal tumor with features of both spiradenoma and cylindroma, the scalp and face being the most common sites. They are considered to arise from pluripotent cells of abortive adnexal primordial tissue. Fine needle aspiration cytology, along with cell block, can give clues regarding the diagnosis. The final diagnosis is made on histopathology, which shows features of both cylindroma and spiradenoma in the same tumor. Multiple spiradenocylindromas can be associated with Brooke-Spiegler syndrome, where malignant transformation has also been reported. We report a case of spiradenocylindroma of the arm in a 50-year- old male and describe the clinical, cytologic, cell block, and histopathologic features.

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Journal
Diagnostic Cytopathology
Published
2025-08-14
DOI
https://doi.org/10.1002/dc.70006
Primary Topic
Cancer and Skin Lesions
Type
article
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article

Spiradenocylindroma: Morphology of a Rare Hybrid Adnexal Tumor

Sudha Sharma, Shailendra Kaushik, Vasudha Sharma
Diagnostic Cytopathology
Cancer and Skin Lesions
article

Spiradenocylindroma: Morphology of a Rare Hybrid Adnexal Tumor

Sudha Sharma, Shailendra Kaushik, Vasudha Sharma
article en

Abstract

Spiradenocylindroma is a rare benign adnexal tumor with features of both spiradenoma and cylindroma, the scalp and face being the most common sites. They are considered to arise from pluripotent cells of abortive adnexal primordial tissue. Fine needle aspiration cytology, along with cell block, can give clues regarding the diagnosis. The final diagnosis is made on histopathology, which shows features of both cylindroma and spiradenoma in the same tumor. Multiple spiradenocylindromas can be associated with Brooke-Spiegler syndrome, where malignant transformation has also been reported. We report a case of spiradenocylindroma of the arm in a 50-year- old male and describe the clinical, cytologic, cell block, and histopathologic features.

Diagnostic CytopathologyVol. 53(11)
General Medical Council (GB), Dr. Mohan's Diabetes Specialities Centre (IN)
Openalex Percentile: Top 58%
Cancer and Skin Lesions
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Spiradenocylindroma: Morphology of a Rare Hybrid Adnexal Tumor — Sudha Sharma, Shailendra Kaushik, et al. · Diagnostic Cytopathology (2025) | TGRS Research Map | TGRS