Case Report: Micronized purified flavonoid fraction [Daflon]-induced bradycardia

We reported a new effect of MPFF as an attenuator of the heart rate. Because venous insufficiency decreased during the observed drug administration period, further studies are needed to examine whether the ability of diosmin and hesperidin to reduce vein disorders is directly linked to their action on heart rate.

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Journal
Frontiers in Pharmacology
Published
2025-08-14
DOI
https://doi.org/10.3389/fphar.2025.1612315
Primary Topic
Cancer Treatment and Pharmacology
Type
article
Field-Weighted Citation Impact
0.00
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article

Case Report: Micronized purified flavonoid fraction [Daflon]-induced bradycardia

Gustavo Uzêda Machado, João Paulo Ferreira Rodrigues, Jonathas Pereira das Graças
Frontiers in Pharmacology
Cancer Treatment and Pharmacology
article

Case Report: Micronized purified flavonoid fraction [Daflon]-induced bradycardia

Gustavo Uzêda Machado, João Paulo Ferreira Rodrigues, Jonathas Pereira das Graças
article en

Abstract

We reported a new effect of MPFF as an attenuator of the heart rate. Because venous insufficiency decreased during the observed drug administration period, further studies are needed to examine whether the ability of diosmin and hesperidin to reduce vein disorders is directly linked to their action on heart rate.

Frontiers in PharmacologyVol. 16
Universidade Estadual de Goiás (BR)
Openalex Percentile: Top 67%
Cancer Treatment and Pharmacology
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