Wuling powder ameliorates diarrhea-predominant irritable bowel syndrome in mice by modulating gut mucosal microbiota and alleviating intestinal inflammation
Wuling powder may inhibit the occurrence of an inflammatory response by reducing the TNF-α and IL-6 levels and increasing the MFGE8 level and may achieve the effect of treating IBS-D by regulating the composition, structure, and function of the intestinal mucosal microbiota, which provides new ideas for the clinical prevention and treatment of IBS-D via Wuling powder.
Authors
- Junxi Shen (ORCID: https://orcid.org/0000-0003-1653-4966)
- Leyao Fang (ORCID: https://orcid.org/0000-0002-8226-2017)
- Ying Cai (ORCID: https://orcid.org/0000-0003-4105-5916)
- Donglin Yu (ORCID: https://orcid.org/0009-0003-3094-7764)
- Qianghong Tian
Institutions
- Hunan University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-08-14
- DOI
- https://doi.org/10.3389/fcimb.2025.1652186
- Citations
- 3
- Primary Topic
- Gastrointestinal motility and disorders
- Type
- article
- Field-Weighted Citation Impact
- 5.43