William S. Sly (1932–2025): A compassionate pioneer in biochemical genetics

William S. Sly, MD (1932-2025) was a biochemical geneticist who received his medical degree from Saint Louis University. He received additional training at the NIH with several members of the National Academy of Science and Nobel Prize winner Marshall Nirenberg. He is best known for discovering mucopolysaccharidosis type VII and developing a Food and Drug Administration-approved treatment for it. He served in several long-term leadership roles and won many accolades, including the Passano Foundation Award and induction into the National Academy of Sciences. Sly was equally well known as a kind and caring person who always made time for family, friends, colleagues, and patients. He is the personification of the caring and compassionate physician-scientist.

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Publication Details

Journal
Proceedings of the National Academy of Sciences
Published
2025-09-03
DOI
https://doi.org/10.1073/pnas.2520590122
Primary Topic
Metabolism and Genetic Disorders
Type
article
Field-Weighted Citation Impact
0.00

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William S. Sly (1932–2025): A compassionate pioneer in biochemical genetics

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article en

Abstract

William S. Sly, MD (1932-2025) was a biochemical geneticist who received his medical degree from Saint Louis University. He received additional training at the NIH with several members of the National Academy of Science and Nobel Prize winner Marshall Nirenberg. He is best known for discovering mucopolysaccharidosis type VII and developing a Food and Drug Administration-approved treatment for it. He served in several long-term leadership roles and won many accolades, including the Passano Foundation Award and induction into the National Academy of Sciences. Sly was equally well known as a kind and caring person who always made time for family, friends, colleagues, and patients. He is the personification of the caring and compassionate physician-scientist.

Proceedings of the National Academy of SciencesVol. 122(36)
Washington University in St. Louis (US), Saint Louis University (US)
Passano Foundation, National Institutes of Health
Openalex Percentile: Top 74%
Metabolism and Genetic Disorders
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