Volunteers Needed: Understanding African Americans’ Perceptions of Clinical Trials and Intentions to Participate

This research highlights how behavioral beliefs and attitudes are positively linked to participation intentions, while subjective norms further reinforce the influence of social pressures on decision-making. Importantly, risk perceptions serve as a significant barrier to participation, particularly among African American women and individuals with lower educational attainment. These findings point to the need for targeted interventions that address specific concerns and build trust through culturally informed, accessible communication. By developing communication strategies that enhance positive beliefs, leverage community influence, and reduce perceived risks, research and healthcare communities can take meaningful steps toward fostering inclusion and trust.