Geometry effects on the boundary-layer profiles of the Keller-Segel system

We consider the boundary-layer problem of a nonlocal semilinear elliptic equation in a bounded smooth domain of all dimensions with the Dirichlet boundary condition, which arises as the stationary problem of the Keller-Segel system with physical boundary conditions describing the boundary-layer formation driven by chemotaxis. Using the Fermi coordinates and delicate analysis with subtle estimates, we rigorously derive the asymptotic expansion of the boundary-layer profile and thickness in terms of the small diffusion rate with coefficients explicitly expressed by the domain geometric properties including mean curvature, volume and surface area. By these expansions, one can explicitly find the joint impact of the mean curvature, surface area and volume of the spatial domain on the boundary-layer steepness and thickness. This seems to be the first result revealing how the boundary-layer profiles depend on the domain geometries for chemotaxis models.

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Journal
Transactions of the American Mathematical Society
Published
2025-09-03
DOI
https://doi.org/10.1090/tran/9528
Primary Topic
Mathematical Biology Tumor Growth
Type
article
Field-Weighted Citation Impact
0.00

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article

Geometry effects on the boundary-layer profiles of the Keller-Segel system

Chiun‐Chang Lee, Sang-Hyuck Moon, Zhi‐An Wang, Wen Yang
Transactions of the American Mathematical Society
Mathematical Biology Tumor Growth
article

Geometry effects on the boundary-layer profiles of the Keller-Segel system

Chiun‐Chang Lee, Sang-Hyuck Moon, Zhi‐An Wang, Wen Yang
article en

Abstract

We consider the boundary-layer problem of a nonlocal semilinear elliptic equation in a bounded smooth domain of all dimensions with the Dirichlet boundary condition, which arises as the stationary problem of the Keller-Segel system with physical boundary conditions describing the boundary-layer formation driven by chemotaxis. Using the Fermi coordinates and delicate analysis with subtle estimates, we rigorously derive the asymptotic expansion of the boundary-layer profile and thickness in terms of the small diffusion rate with coefficients explicitly expressed by the domain geometric properties including mean curvature, volume and surface area. By these expansions, one can explicitly find the joint impact of the mean curvature, surface area and volume of the spatial domain on the boundary-layer steepness and thickness. This seems to be the first result revealing how the boundary-layer profiles depend on the domain geometries for chemotaxis models.

Transactions of the American Mathematical SocietyVol. 378(12)
Hong Kong Polytechnic University (HK), University of Macau (MO), National Tsing Hua University (TW), Pusan National University (KR)
National Natural Science Foundation of China, Ministry of Science and Technology, Taiwan, Universidade de Macau, Ministry of Science and ICT, South Korea, University Research Committee, University of Hong Kong, National Key Research and Development Program of China
Openalex Percentile: Top 73%
Mathematical Biology Tumor Growth
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Geometry effects on the boundary-layer profiles of the Keller-Segel system — Chiun‐Chang Lee, Sang-Hyuck Moon, et al. · Transactions of the American Mathematical Society (2025) | TGRS Research Map | TGRS