Increased 68Ga-FAPI Uptake of Ureteric Fibroepithelial Polyp and Costal Cyst Mimicking Malignancy With Bone Metastasis

A 70-year-old man presented with progressive dysuria. 18 F-FDG PET/CT showed no abnormal metabolic activity. 68 Ga-FAPI PET/CT revealed intense 68 Ga-FAPI in the lower left ureter and the left rib, mimicking malignancy with bone metastasis. However, postoperative pathological biopsy demonstrated the diagnosis of ureteric fibroepithelial polyp. In addition, the prior CT scan confirmed a bone cyst. Our case highlights the necessity of reviewing the patient's skeletal history when encountering a primary tumor with FAPI uptake and a concurrent FAPI-avid bone lesion.

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Publication Details

Journal
Clinical Nuclear Medicine
Published
2025-09-01
DOI
https://doi.org/10.1097/rlu.0000000000006097
Primary Topic
Peptidase Inhibition and Analysis
Type
article
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article

Increased 68Ga-FAPI Uptake of Ureteric Fibroepithelial Polyp and Costal Cyst Mimicking Malignancy With Bone Metastasis

Lu Zhang, Guojian Zhang, Xiang Lin
Clinical Nuclear Medicine
Peptidase Inhibition and Analysis
article

Increased 68Ga-FAPI Uptake of Ureteric Fibroepithelial Polyp and Costal Cyst Mimicking Malignancy With Bone Metastasis

Lu Zhang, Guojian Zhang, Xiang Lin
article en

Abstract

A 70-year-old man presented with progressive dysuria. 18 F-FDG PET/CT showed no abnormal metabolic activity. 68 Ga-FAPI PET/CT revealed intense 68 Ga-FAPI in the lower left ureter and the left rib, mimicking malignancy with bone metastasis. However, postoperative pathological biopsy demonstrated the diagnosis of ureteric fibroepithelial polyp. In addition, the prior CT scan confirmed a bone cyst. Our case highlights the necessity of reviewing the patient's skeletal history when encountering a primary tumor with FAPI uptake and a concurrent FAPI-avid bone lesion.

Clinical Nuclear MedicineVol. 50(12)
Inner Mongolia Medical College Hospital (CN), Inner Mongolia Medical University (CN)
Openalex Percentile: Top 67%
Peptidase Inhibition and Analysis
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Increased 68Ga-FAPI Uptake of Ureteric Fibroepithelial Polyp and Costal Cyst Mimicking Malignancy With Bone Metastasis — Lu Zhang, Guojian Zhang, et al. · Clinical Nuclear Medicine (2025) | TGRS Research Map | TGRS