Comparison of 68Ga-FAPI-04 and 18F-FDG in Primary Splenic Angiosarcoma

Primary splenic angiosarcoma is a rare, aggressive tumor, characterized by rapid metastasis and poor prognosis. Herein, we report a case of 18F-FDG and 68Ga-FAPI-04 PET/CT imaging in a 57-year-old man with primary splenic angiosarcoma. 68Ga-FAPI-04 PET/CT presented much higher uptake in the lesions compared with 18F-FDG PET/CT, showing better diagnostic performance. Our case demonstrated the characteristics of 68Ga-FAPI-04 PET/CT in primary splenic angiosarcoma and suggested its potential as a more promising alternative to 18F-FDG PET/CT for diagnosis and a useful tool for clinical management.