Heterotopic Pancreas Mimicking Gastrointestinal Stromal Tumor on 68Ga-NOTA-RM26 PET/CT

Heterotopic pancreas is a congenital malformation of various shapes and origins and is usually asymptomatic, which can simulate benign tumors on imaging, so diagnosis usually requires biopsy or surgical resection. We present a young woman with abdominal distension who was found to have a gastric mass that was suspected to be a gastrointestinal stromal tumor (GIST) by gastroscopy and enhanced CT. 68 Ga-NOTA-RM26 PET/CT, a novel imaging modality targeting the gastrin-releasing peptide receptor (GRPR), also showed intense uptake in the mass. Pathology results of the resected mass demonstrated pancreatic tissue, supporting the diagnosis of heterotopic pancreas.