Differences in incidence of post-induction hypotension depending on the time of day: a post-hoc propensity score matched analysis
Post-induction hypotension was more frequent in the morning compared to the afternoon. While this finding is in line with the presumed physiological mechanisms, it may be affected by unmeasured confounding. These findings should be replicated in larger, preferably randomised, studies to confirm whether a causal relationship between the time of day of anaesthesia induction and post-induction hypotension exists. Clinical registration number This study was registered in the Dutch Medical Research in Humans (OMON) register on 18 June 2019 (ID: NL7810). The study was approved by the Medical Ethics Committee of the Amsterdam UMC, location AMC, Netherlands in December 2018 (NL 6748.018.18; 2018).
Authors
- Mark L. van Zuylen (ORCID: https://orcid.org/0000-0001-9439-6664)
- Eline Kho (ORCID: https://orcid.org/0000-0003-2001-4111)
- Jimmy Schenk (ORCID: https://orcid.org/0000-0003-0570-0017)
- Dirk Jan Stenvers (ORCID: https://orcid.org/0000-0002-9519-5140)
- Lotte E. Terwindt (ORCID: https://orcid.org/0000-0002-8150-9348)
- Ward H. van der Ven (ORCID: https://orcid.org/0000-0003-0508-0620)
- Arjen J. G. Meewisse (ORCID: https://orcid.org/0009-0004-4268-4401)
- Johan T.M. Tol
- Denise Petra Veelo (ORCID: https://orcid.org/0000-0001-6196-1671)
- Alexander P. J. Vlaar (ORCID: https://orcid.org/0000-0002-3453-7186)
- Björn van der Ster
- Vincent C Kurucz
- Jeroen Hermanides
- Sijm H. Noteboom (ORCID: https://orcid.org/0000-0002-2443-0764)
Institutions
- Amsterdam Neuroscience (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- Journal of Clinical Anesthesia
- Published
- 2025-09-03
- DOI
- https://doi.org/10.1016/j.jclinane.2025.111984
- Citations
- 1
- Primary Topic
- Heart Rate Variability and Autonomic Control
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- Edwards Lifesciences