Identification of Metabolomics Profile in Elderly Patients at the End Stage of Heart Failure
Carnitine, symmetric dimethylarginine, urea, and tryptophan appear to be critical biomarkers for monitoring terminal stages in HF. Our results suggest that myocardial energy metabolism and renal dysfunction are associated with changes in the metabolome.
Authors
- Yasutaka Oguchi
- Soichiro Ebisawa (ORCID: https://orcid.org/0000-0002-6146-9959)
- Tatsuya Saigusa (ORCID: https://orcid.org/0000-0002-1856-1047)
- Sho Suzuki (ORCID: https://orcid.org/0000-0001-9058-9258)
- Koichiro Kuwahara (ORCID: https://orcid.org/0000-0003-2670-7170)
- Koji Yoshie (ORCID: https://orcid.org/0000-0002-2378-2768)
- Tamon Kato (ORCID: https://orcid.org/0000-0001-5350-4083)
- Yukari Okuma
- Kazuhiro Kimura (ORCID: https://orcid.org/0000-0002-2502-6149)
- Ayako Okada (ORCID: https://orcid.org/0000-0002-8342-1163)
- Hirohiko Motoki (ORCID: https://orcid.org/0000-0002-5219-6856)
- Ken Nishikawa (ORCID: https://orcid.org/0000-0001-9585-1171)
- Yasushi Ueki (ORCID: https://orcid.org/0000-0003-4630-9815)
- Masatoshi Minamisawa
- M Kanai
Institutions
- Shinshu University (JP)
Publication Details
- Journal
- Circulation Journal
- Published
- 2025-09-03
- DOI
- https://doi.org/10.1253/circj.cj-25-0278
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00