Resveratrol primed adipose stem cell-derived exosomes alleviate intestinal ischemia reperfusion injury by regulating macrophage polarization
We demonstrated that RSV-primed Exo effectively suppress intestinal barrier dysfunctions and the dysregulation of mucosal immune responses. The results highlight that RSV-primed Exo could be novel and promising candidate for prevention of intestinal IRI.
Authors
- Qiufeng Peng
- Kai Ye (ORCID: https://orcid.org/0000-0002-2851-6741)
- Hillary Hei (ORCID: https://orcid.org/0000-0002-2381-6817)
- Hui Xue (ORCID: https://orcid.org/0000-0002-2093-2839)
- Xiang Li (ORCID: https://orcid.org/0000-0002-7015-6006)
- Hua Guo (ORCID: https://orcid.org/0000-0002-0974-583X)
- Hao Wang (ORCID: https://orcid.org/0000-0001-9115-1290)
- Zhanwei Zhang
Institutions
- Tianjin Medical University General Hospital (CN)
- Tianjin Fourth Central Hospital (CN)
Publication Details
- Journal
- International Immunopharmacology
- Published
- 2025-09-03
- DOI
- https://doi.org/10.1016/j.intimp.2025.115481
- Citations
- 1
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.81