Interactions between the intestinal microbiome and host genes in regulating vibriosis resistance in Cynoglossus semilaevis
The results of this study indicate that <i>V. harveyi</i> infection severely damages the intestinal tissue and substantially alters the composition of intestinal microbiome and the expression of host genes, especially in susceptible individuals. Strong gene-microbe correlations may imply that the intestinal microbiome may interact with host genes to collectively regulate the vibriosis resistance in Chinese tongue sole, but the causality between them remains unestablished and requires further validation.
Authors
- Zhihong Liu (ORCID: https://orcid.org/0000-0002-6221-769X)
- Tao Yang (ORCID: https://orcid.org/0000-0003-2355-1270)
- Han Huizong (ORCID: https://orcid.org/0000-0002-7097-042X)
- Tengteng Wang (ORCID: https://orcid.org/0000-0001-9001-186X)
- Xiaoqing Xi (ORCID: https://orcid.org/0000-0001-5969-261X)
- Weiwei Zheng (ORCID: https://orcid.org/0000-0002-8657-4210)
- Yaning Wang (ORCID: https://orcid.org/0000-0002-0999-0499)
- Yadong Chen (ORCID: https://orcid.org/0009-0000-5523-593X)
- Dong Xu
Institutions
- Institute of Economic Development (GB)
- Qingdao National Laboratory for Marine Science and Technology (CN)
- Shandong Marine Resource and Environment Research Institute (CN)
- Rongcheng City People's Hospital (CN)
- Chinese Academy of Fishery Sciences (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-09-03
- DOI
- https://doi.org/10.3389/fimmu.2025.1644885
- Primary Topic
- Vibrio bacteria research studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00