Synergistic role of blood-labyrinth barrier permeability and endolymphatic hydrops: a comparative perspective in Ménière’s disease and vestibular migraine

Delayed gadolinium-enhanced MRI of the inner ear facilitates the differentiation between MD and VM. The combination of EH, SIR, and c-SIR AI demonstrates excellent diagnostic performance. Notably, elevated SIR shows the strongest correlation with high-frequency hearing impairment, while cochlear EH primarily contributes to low- and mid-frequency hearing loss. By integrating imaging findings with audiological profiles, clinicians can accurately characterize cochlear pathology, enabling the development of tailored treatment strategies.

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Publication Details

Journal
Frontiers in Neurology
Published
2025-09-03
DOI
https://doi.org/10.3389/fneur.2025.1667277
Citations
2
Primary Topic
Vestibular and auditory disorders
Type
article
Field-Weighted Citation Impact
1.68
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article

Synergistic role of blood-labyrinth barrier permeability and endolymphatic hydrops: a comparative perspective in Ménière’s disease and vestibular migraine

Yuanyuan Sun, Bo Shen, Shuning Sun, Yaoheng Zhang et al.
2 citations
Frontiers in Neurology
Vestibular and auditory disorders
1.68
article

Synergistic role of blood-labyrinth barrier permeability and endolymphatic hydrops: a comparative perspective in Ménière’s disease and vestibular migraine

Yuanyuan Sun, Bo Shen, Shuning Sun, Yaoheng Zhang, Wenbo Peng, Yanlu Jia, Hui Li, Chunling Liu, Haozhe Yin, Yifan Zheng
article en
2 citations

Abstract

Delayed gadolinium-enhanced MRI of the inner ear facilitates the differentiation between MD and VM. The combination of EH, SIR, and c-SIR AI demonstrates excellent diagnostic performance. Notably, elevated SIR shows the strongest correlation with high-frequency hearing impairment, while cochlear EH primarily contributes to low- and mid-frequency hearing loss. By integrating imaging findings with audiological profiles, clinicians can accurately characterize cochlear pathology, enabling the development of tailored treatment strategies.

Frontiers in NeurologyVol. 16
First Affiliated Hospital of Jiamusi University (CN), Second Affiliated Hospital of Zhengzhou University (CN)
Openalex Percentile: Top 14%
Vestibular and auditory disorders
1.68
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