Evaluation of degree centrality and neurological outcomes in patients with herpes simplex encephalitis
Cerebral intrinsic connectivity changes as assessed by DC in HSE were associated with neurological deficits (as assessed by the NIHSS score), level of consciousness (as assessed by the GCS score), and functional disability. Our findings provide novel insights into the neural mechanisms underlying HSE-related neurological deficits and inform the development of targeted therapeutic interventions.
Authors
- Yinhai Chen
- Dongzhi Liu
- Jingchen Zhang (ORCID: https://orcid.org/0000-0003-3132-916X)
- Jueyue Yan (ORCID: https://orcid.org/0000-0001-5833-3578)
- Dong Zhu (ORCID: https://orcid.org/0000-0002-0826-6423)
- Xiaoyu Liu (ORCID: https://orcid.org/0000-0002-5878-5491)
- Haolong He
Institutions
- Quzhou City People's Hospital (CN)
- Xian Central Hospital (CN)
- Shaoxing Second Hospital (CN)
- Shaoxing People's Hospital (CN)
- First Affiliated Hospital Zhejiang University (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-09-03
- DOI
- https://doi.org/10.3389/fneur.2025.1588294
- Primary Topic
- Herpesvirus Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Zhejiang Medical Association
- Natural Science Foundation of Zhejiang Province