Hyaluronan in the pathogenesis of lung fibrosis associated to autoimmune pulmonary alveolar proteinosis (aPAP)
Our results seem to indicate that a robust HA production contributes to the chronic inflammatory and micro-injury to the alveolar epithelium. The high specificity of HA highlights its utility as a prognostic biomarker of aPAP-associated fibrosis.
Authors
- Annalisa De Silvestri (ORCID: https://orcid.org/0000-0003-3128-8441)
- Matteo Della Zoppa (ORCID: https://orcid.org/0000-0001-7764-6385)
- Laura Ciardelli (ORCID: https://orcid.org/0000-0002-8504-9609)
- Angelo Guido Corsico (ORCID: https://orcid.org/0000-0002-8716-4694)
- Michele Zorzetto (ORCID: https://orcid.org/0000-0002-7826-3666)
- Francesca Mariani (ORCID: https://orcid.org/0000-0001-9500-6082)
- Sara Lettieri (ORCID: https://orcid.org/0009-0005-2404-2082)
- Ilaria Campo (ORCID: https://orcid.org/0000-0002-4423-2482)
- Riccardo Albertini (ORCID: https://orcid.org/0000-0003-0462-0867)
- Vincenzo Alfredo Marando
- Raffaele Gentile
Institutions
- University of Pavia (IT)
- Policlinico San Matteo Fondazione (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-09-03
- DOI
- https://doi.org/10.3389/fmed.2025.1650830
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00