Supplemental Figure 4 from Genetic and Phenotypic Correlates of Clinical Outcomes with Venetoclax in Acute Myeloid Leukemia: The GEN-PHEN-VEN Study
<p>Overall survival in the subgroup of patients not receiving allogeneic cell transplantation (HCT) based on (A) monocytic vs. non-monocytic differentiation, (B) monocytic differentiation and NPM1 mutation status, (C) in the subgroup of patients with RAS pathway and FLT3-ITD mutations (K/NRAS, PTPN11, FLT3-ITD) and wild-type IDH1/2, NPM1, and TP53; (D) within the patient subgroup classified as mPRS higher-benefit (wild-type for FLT3, N/KRAS and TP53). Reported p-values utilized the cox model Wald test.</p>
Authors
- Gaspar Aspas Requena (ORCID: https://orcid.org/0000-0001-9033-575X)
- Aishwarya Sahasrabudhe (ORCID: https://orcid.org/0000-0002-8793-8135)
- Elie Traer (ORCID: https://orcid.org/0000-0001-8844-2345)
- Maël Heiblig (ORCID: https://orcid.org/0000-0003-1682-8657)
- Emmanuelle Tavernier (ORCID: https://orcid.org/0000-0002-1447-8721)
- Brandon Hayes‐Lattin (ORCID: https://orcid.org/0000-0002-4380-4573)
- Daniel T. Peters (ORCID: https://orcid.org/0000-0002-4655-0994)
- Christopher A. Eide (ORCID: https://orcid.org/0000-0001-8835-8928)
- Theodore P. Braun (ORCID: https://orcid.org/0000-0002-6248-2143)
- Daniel A. Pollyea (ORCID: https://orcid.org/0000-0001-6519-4860)
- Ronan Swords (ORCID: https://orcid.org/0000-0003-3319-1870)
- Jessica Leonard (ORCID: https://orcid.org/0000-0001-5576-0048)
- Ashley M. Eckel (ORCID: https://orcid.org/0000-0002-2130-4965)
- Joshua F. Zeidner (ORCID: https://orcid.org/0000-0002-9014-1514)
- Arpita P. Gandhi (ORCID: https://orcid.org/0000-0002-9762-8069)
- Maria L. Amaya (ORCID: https://orcid.org/0000-0001-9503-5019)
- Jennifer N. Saultz (ORCID: https://orcid.org/0000-0003-0024-9466)
- Nicola Long (ORCID: https://orcid.org/0000-0002-9010-8167)
- Andy Kaempf (ORCID: https://orcid.org/0000-0001-9425-6936)
- Gabrielle Meyers (ORCID: https://orcid.org/0000-0001-7821-8745)
- Jeffrey Tyner (ORCID: https://orcid.org/0000-0002-2133-0960)
- Michael R. Loken (ORCID: https://orcid.org/0000-0002-0335-9065)
- Christine M. McMahon (ORCID: https://orcid.org/0000-0001-9745-9595)
- Rachel J. Cook (ORCID: https://orcid.org/0000-0001-7005-036X)
- Stephen E. Kurtz (ORCID: https://orcid.org/0000-0003-4762-389X)
- Anupriya Agarwal (ORCID: https://orcid.org/0000-0002-8319-6162)
- Wei Xie (ORCID: https://orcid.org/0000-0003-1815-7666)
- Richard T. Maziarz (ORCID: https://orcid.org/0000-0002-8184-7099)
- Curtis A. Lachowiez (ORCID: https://orcid.org/0000-0001-8506-0624)
- Jacob Fang (ORCID: https://orcid.org/0000-0003-4422-1449)
- Fangyan Dai (ORCID: https://orcid.org/0000-0003-3494-4547)
- Amenech B. Ashango
Publication Details
- Published
- 2025-09-03
- DOI
- https://doi.org/10.1158/2643-3230.30040836
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00