Association between blood cobalt ion concentrations and anemia and cardiovascular diseases: novel evidence of toxicity resulting from metal implants
Metal object-derived cobalt exposure demonstrates significant dose-dependent associations with anemia and multiple CVD subtypes. These findings underscore the systemic toxicity of cobalt ions and advocate for enhanced clinical surveillance of blood cobalt levels in patients with metal implants.
Authors
- Julie Xiao (ORCID: https://orcid.org/0000-0002-5997-0031)
- Yanguo Qin (ORCID: https://orcid.org/0000-0003-3296-3779)
- Shenghao Xu (ORCID: https://orcid.org/0000-0003-3908-1525)
- Bo Chen (ORCID: https://orcid.org/0000-0002-9926-4377)
- Hao Wang (ORCID: https://orcid.org/0000-0001-7661-3688)
- Xingkun Tang
Institutions
- Jilin University (CN)
- Second Affiliated Hospital of Jilin University (CN)
- East Asia Research (SG)
- Union Hospital (CN)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2025-09-03
- DOI
- https://doi.org/10.3389/fnut.2025.1614771
- Citations
- 2
- Primary Topic
- Orthopaedic implants and arthroplasty
- Type
- article
- Field-Weighted Citation Impact
- 4.01
Funders
- National Natural Science Foundation of China
- Department of Finance of Jilin Province