Exploring plasticisers-osteoporosis links and mechanisms: a cohort and network toxicology study
MEHP exposure is positively associated with OP risk, with CTSD, VCP, and the apoptosis pathway potentially playing key roles in impairing BMSC osteogenesis.
Authors
- Zhengjiang Li (ORCID: https://orcid.org/0000-0002-6639-3420)
- Zhenshan Du
- Shuxing Xing (ORCID: https://orcid.org/0000-0001-7166-7097)
- Stephen Bao (ORCID: https://orcid.org/0000-0001-7507-2402)
- Xingyao Yang
- Xin Wang (ORCID: https://orcid.org/0000-0001-6588-276X)
Institutions
- North Sichuan Medical University (CN)
- Beijing Institute of Education (CN)
- Chengdu Fifth People's Hospital (CN)
- Institute of Basic Medical Sciences of the Chinese Academy of Medical Sciences
Publication Details
- Journal
- Frontiers in Toxicology
- Published
- 2025-09-03
- DOI
- https://doi.org/10.3389/ftox.2025.1617663
- Citations
- 1
- Primary Topic
- Computational Drug Discovery Methods
- Type
- article
- Field-Weighted Citation Impact
- 1.50
Funders
- Department of Science and Technology of Sichuan Province
- Chengdu Science and Technology Bureau