Cilostazol-inhibited RhoA/NF-κB signaling mitigates hippocampal inflammation and post-stroke depression
Cilostazol may alleviate hippocampal inflammation by inhibiting RhoA/NF-κB signaling pathway activation in the microglia, providing neuronal protection and PSD prevention effects.
Authors
- Yichen Li (ORCID: https://orcid.org/0009-0003-3720-9334)
- Chaozhi Tang (ORCID: https://orcid.org/0000-0002-4624-716X)
- Yuling Zhang (ORCID: https://orcid.org/0000-0001-8805-5249)
- Tingting Ji (ORCID: https://orcid.org/0000-0001-5566-4574)
- Xiying Tan (ORCID: https://orcid.org/0009-0002-2604-9948)
- Yafang Wu
Institutions
- Liupanshui Normal University (CN)
- Xinxiang Central Hospital (CN)
- Henan Normal University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-09-03
- DOI
- https://doi.org/10.3389/fphar.2025.1643343
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Henan Normal University
- Liupanshui Normal University