Diet-mediated bioenergetic flux: A double-edged sword for health and diseases

Bioenergetics has emerged as a critical lens for understanding health promotion and disease pathogenesis, thus offering potential biomarkers for various energy-related diseases and crafting innovative interventional strategies. This article comprehensively covers the significant role of bioenergetic processes in health, focusing on the systemic implications of cellular energy dynamics, such as ATP production, mitochondrial efficacy, redox balance, and metabolic adaptability. Through highlighting the complexity of these processes, this article underscores the collective impact on health, suggesting that deeper insight into bioenergetic flux can inform both diagnostic and therapeutic advancements. Moreover, this article explores how diets can modulate energy balance and bioenergetic flow, offering innovative approaches for health promotion through precision nutrition and food-based therapeutic strategies.