De Novo Immune Induction After COVID‐19 Vaccination Under B‐Cell Depletion Is Characterized by Robust T‐Cellular Immunity in Patients With Inflammatory Central Nervous System Disease
Despite limited ability of B-cell depleted patients to mount a humoral immune response after multiple doses of SARS-CoV-2 mRNA vaccination, the vaccine-induced T-cell response is robust, which may have implications for protection against severe disease.
Authors
- Martina Sester (ORCID: https://orcid.org/0000-0001-5482-0002)
- Franziska Hielscher (ORCID: https://orcid.org/0000-0001-8527-8412)
- Mathias Fousse (ORCID: https://orcid.org/0000-0001-5489-1492)
- Tina Schmidt (ORCID: https://orcid.org/0000-0001-7929-5283)
- Verena Klemis (ORCID: https://orcid.org/0000-0002-5636-1273)
- Rebecca Urschel (ORCID: https://orcid.org/0009-0008-2677-5118)
- Saskia Bronder (ORCID: https://orcid.org/0000-0001-5863-1268)
- Klaus Faßbender (ORCID: https://orcid.org/0000-0003-3596-868X)
- Urban Sester (ORCID: https://orcid.org/0000-0003-4007-5595)
Institutions
- Klinikum Esslingen (DE)
- Saarland University (DE)
Publication Details
- Journal
- Brain and Behavior
- Published
- 2025-09-01
- DOI
- https://doi.org/10.1002/brb3.70849
- Citations
- 1
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 1.40
Funders
- Bundesministerium für Bildung und Forschung