A Systematic Review of the Latest Treatments and Risk Factors in Pregnant Women with Systemic Lupus Erythematosus

This paper reviews the important medical problem of women with systemic lupus erythematosus during pregnancy.As an autoimmune disease, lupus can significantly impact the health of both mother and baby, making these pregnancies high-risk and requiring close monitoring as well as a team approach to care.This article will also present the most frequent problems encountered during pregnancy in these women, such as flares of the disease, obstetric complications, and fetal risk.Special attention is given to the use of medications.The article discusses drugs which can be used safely and are effective during pregnancy, those that are not harmful to the fetus and can keep the progress of the disease in check through the mother.Moreover, it will review the current state of treatment, and particularly therapeutic approaches developed over the last 10 years, for which scientific evidence and clinical experience are available.The purpose of this review is to emphasize the special difficulties encountered when treating pregnant women with SLE and to present clinical strategies that can improve the likelihood of a healthy pregnancy and delivery for both the mother and infant.

Authors

Publication Details

Journal
Medical Science
Published
2025-08-30
DOI
https://doi.org/10.54905/disssi.v29i162.e147ms3633
Primary Topic
Systemic Lupus Erythematosus Research
Type
article
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article

A Systematic Review of the Latest Treatments and Risk Factors in Pregnant Women with Systemic Lupus Erythematosus

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Systemic Lupus Erythematosus Research
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A Systematic Review of the Latest Treatments and Risk Factors in Pregnant Women with Systemic Lupus Erythematosus

M Marciniak, Natalia Sioch, Julia Krotofil, Julia Sztubińska, Maciej Trzciński, Kamil Nieczaj, Marta Tortyna, Danuta Borowska, Julia Urbańska, Paula Szarek, Olga Samsel
article en

Abstract

This paper reviews the important medical problem of women with systemic lupus erythematosus during pregnancy.As an autoimmune disease, lupus can significantly impact the health of both mother and baby, making these pregnancies high-risk and requiring close monitoring as well as a team approach to care.This article will also present the most frequent problems encountered during pregnancy in these women, such as flares of the disease, obstetric complications, and fetal risk.Special attention is given to the use of medications.The article discusses drugs which can be used safely and are effective during pregnancy, those that are not harmful to the fetus and can keep the progress of the disease in check through the mother.Moreover, it will review the current state of treatment, and particularly therapeutic approaches developed over the last 10 years, for which scientific evidence and clinical experience are available.The purpose of this review is to emphasize the special difficulties encountered when treating pregnant women with SLE and to present clinical strategies that can improve the likelihood of a healthy pregnancy and delivery for both the mother and infant.

Medical ScienceVol. 29(162)
Openalex Percentile: Top 65%
Systemic Lupus Erythematosus Research
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