The Cardiovascular Paradox of Marathon Running: Acute Stress, Chronic Adaptations, and Longterm Health Implications

This article explores the intricate relationship between marathon running and cardiovascular health.As participation in marathons increases year by year, scientific research into the acute responses and chronic adaptations of the cardiovascular system is becoming more common.Acute cardiac responses contain temporary elevations in cardiac biomarkers and changes in cardiac function, which especially affect the right ventricle.However, chronic adaptations include beneficial cardiac remodeling.The review analyzes evidence from numerous studies documenting these cardiovascular changes, exploring both potential concerns and substantial benefits.Although numerous scientific articles suggest possible risks associated with extreme endurance training, epidemiological data shows that marathon runners have a significantly lower risk of cardiovascular disease.This study investigates impact on the left and right ventricular chambers, vascular function, autonomic regulation and correlation between exercise intensity and cardiovascular health.The study also discusses the clinical implications of screening, monitoring, and recovery protocols, providing a balanced perspective on the cardiovascular impact of marathon participation.Furthermore, the study combines the current evidence to inform clinical practice, that with proper preparation and medical screening, marathon running can be advantageous for cardiovascular health.

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Publication Details

Journal
Medical Science
Published
2025-08-30
DOI
https://doi.org/10.54905/disssi.v29i162.e133ms3614
Primary Topic
Cardiovascular Effects of Exercise
Type
article
Field-Weighted Citation Impact
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article

The Cardiovascular Paradox of Marathon Running: Acute Stress, Chronic Adaptations, and Longterm Health Implications

Tomasz Czapiewski, Maciej Szymczak, Wiktor Szymajda, Lidia Żyła et al.
Medical Science
Cardiovascular Effects of Exercise
article

The Cardiovascular Paradox of Marathon Running: Acute Stress, Chronic Adaptations, and Longterm Health Implications

Tomasz Czapiewski, Maciej Szymczak, Wiktor Szymajda, Lidia Żyła, Aleksandra Trojańska
article en

Abstract

This article explores the intricate relationship between marathon running and cardiovascular health.As participation in marathons increases year by year, scientific research into the acute responses and chronic adaptations of the cardiovascular system is becoming more common.Acute cardiac responses contain temporary elevations in cardiac biomarkers and changes in cardiac function, which especially affect the right ventricle.However, chronic adaptations include beneficial cardiac remodeling.The review analyzes evidence from numerous studies documenting these cardiovascular changes, exploring both potential concerns and substantial benefits.Although numerous scientific articles suggest possible risks associated with extreme endurance training, epidemiological data shows that marathon runners have a significantly lower risk of cardiovascular disease.This study investigates impact on the left and right ventricular chambers, vascular function, autonomic regulation and correlation between exercise intensity and cardiovascular health.The study also discusses the clinical implications of screening, monitoring, and recovery protocols, providing a balanced perspective on the cardiovascular impact of marathon participation.Furthermore, the study combines the current evidence to inform clinical practice, that with proper preparation and medical screening, marathon running can be advantageous for cardiovascular health.

Medical ScienceVol. 29(162)
Openalex Percentile: Top 64%
Cardiovascular Effects of Exercise
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The Cardiovascular Paradox of Marathon Running: Acute Stress, Chronic Adaptations, and Longterm Health Implications — Tomasz Czapiewski, Maciej Szymczak, et al. · Medical Science (2025) | TGRS Research Map | TGRS