PERSONALIZED APPROACH TO THE PROGNOSIS AND PREVENTION OF INTRA-ABDOMINAL ADHESIONS AFTER APPENDECTOMY
Rationale : The incidence of acute appendicitis is 708 cases per 10000 population. Postoperative complications after open appendectomy were 2.35 to 10%, after laparoscopic appendectomy from 4.9% to 6.2%. Abdominal interventions are accompanied by the development of intra-abdominal adhesions in 14.0% of patients, after repeated interventions – in 90.0-96.0% of the operated patients. Purpose : To determine the efficacy of anti-adhesion therapy after appendectomy. Materials and methods : 60 patients with acute appendicitis who underwent open appendectomy. Men – 19 (31.7%), women – 41 (68.3%). The control group consisted of 30 (50%) patients who did not undergo prevention of intra-abdominal adhesions in the postoperative period, and another 30 (50%) patients who received anti-adhesion therapy (main group). To calculate the risk of intra-abdominal adhesions after ppendectomy, we have developed an “Assistant program for determining the effectiveness of the treatment method and preventing the development of postoperative intra-abdominal adhesions”. Results: By the method of rating testing, it was established that the highest risk of developing postoperative intra-abdominal adhesions is present in patients who do not receive a set of anti-adhesion measures. Anti-adhesion therapy in patients after appendectomy reduces the risk of intra-abdominal adhesions by 1.97 times, improves the quality of life of operated patients. Conclusion: When performing abdominal operations, it is necessary to form groups of patients with a tendency to the formation of intra-abdominal adhesions, for whom anti-adhesion therapy is indicated in order to reduce the risk of developing an adhesive process in the abdominal cavity.
Authors
- M. B. Uzdenov (ORCID: https://orcid.org/0000-0002-0077-9013)
- Peter Lavreshin
- Vakhtang Gobejishvili
- Sofia Korablina (ORCID: https://orcid.org/0000-0002-5113-2543)
- Marat Kazbekovich Chotchaev (ORCID: https://orcid.org/0000-0002-6546-8646)
- P. I. Chumakov
Institutions
- Sechenov University (RU)
Publication Details
- Journal
- Bulletin of Pirogov National Medical & Surgical Center
- Published
- 2025-08-29
- DOI
- https://doi.org/10.25881/20728255_2025_20_3_64
- Primary Topic
- Appendicitis Diagnosis and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00