PERSONALIZED APPROACH TO THE PROGNOSIS AND PREVENTION OF INTRA-ABDOMINAL ADHESIONS AFTER APPENDECTOMY

Rationale : The incidence of acute appendicitis is 708 cases per 10000 population. Postoperative complications after open appendectomy were 2.35 to 10%, after laparoscopic appendectomy from 4.9% to 6.2%. Abdominal interventions are accompanied by the development of intra-abdominal adhesions in 14.0% of patients, after repeated interventions – in 90.0-96.0% of the operated patients. Purpose : To determine the efficacy of anti-adhesion therapy after appendectomy. Materials and methods : 60 patients with acute appendicitis who underwent open appendectomy. Men – 19 (31.7%), women – 41 (68.3%). The control group consisted of 30 (50%) patients who did not undergo prevention of intra-abdominal adhesions in the postoperative period, and another 30 (50%) patients who received anti-adhesion therapy (main group). To calculate the risk of intra-abdominal adhesions after ppendectomy, we have developed an “Assistant program for determining the effectiveness of the treatment method and preventing the development of postoperative intra-abdominal adhesions”. Results: By the method of rating testing, it was established that the highest risk of developing postoperative intra-abdominal adhesions is present in patients who do not receive a set of anti-adhesion measures. Anti-adhesion therapy in patients after appendectomy reduces the risk of intra-abdominal adhesions by 1.97 times, improves the quality of life of operated patients. Conclusion: When performing abdominal operations, it is necessary to form groups of patients with a tendency to the formation of intra-abdominal adhesions, for whom anti-adhesion therapy is indicated in order to reduce the risk of developing an adhesive process in the abdominal cavity.

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Journal
Bulletin of Pirogov National Medical & Surgical Center
Published
2025-08-29
DOI
https://doi.org/10.25881/20728255_2025_20_3_64
Primary Topic
Appendicitis Diagnosis and Management
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article
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article

PERSONALIZED APPROACH TO THE PROGNOSIS AND PREVENTION OF INTRA-ABDOMINAL ADHESIONS AFTER APPENDECTOMY

M. B. Uzdenov, Peter Lavreshin, Vakhtang Gobejishvili, Sofia Korablina et al.
Bulletin of Pirogov National Medical & Surgical Center
Appendicitis Diagnosis and Management
article

PERSONALIZED APPROACH TO THE PROGNOSIS AND PREVENTION OF INTRA-ABDOMINAL ADHESIONS AFTER APPENDECTOMY

M. B. Uzdenov, Peter Lavreshin, Vakhtang Gobejishvili, Sofia Korablina, Marat Kazbekovich Chotchaev, P. I. Chumakov
article en

Abstract

Rationale : The incidence of acute appendicitis is 708 cases per 10000 population. Postoperative complications after open appendectomy were 2.35 to 10%, after laparoscopic appendectomy from 4.9% to 6.2%. Abdominal interventions are accompanied by the development of intra-abdominal adhesions in 14.0% of patients, after repeated interventions – in 90.0-96.0% of the operated patients. Purpose : To determine the efficacy of anti-adhesion therapy after appendectomy. Materials and methods : 60 patients with acute appendicitis who underwent open appendectomy. Men – 19 (31.7%), women – 41 (68.3%). The control group consisted of 30 (50%) patients who did not undergo prevention of intra-abdominal adhesions in the postoperative period, and another 30 (50%) patients who received anti-adhesion therapy (main group). To calculate the risk of intra-abdominal adhesions after ppendectomy, we have developed an “Assistant program for determining the effectiveness of the treatment method and preventing the development of postoperative intra-abdominal adhesions”. Results: By the method of rating testing, it was established that the highest risk of developing postoperative intra-abdominal adhesions is present in patients who do not receive a set of anti-adhesion measures. Anti-adhesion therapy in patients after appendectomy reduces the risk of intra-abdominal adhesions by 1.97 times, improves the quality of life of operated patients. Conclusion: When performing abdominal operations, it is necessary to form groups of patients with a tendency to the formation of intra-abdominal adhesions, for whom anti-adhesion therapy is indicated in order to reduce the risk of developing an adhesive process in the abdominal cavity.

Bulletin of Pirogov National Medical & Surgical CenterVol. 20(3)
Sechenov University (RU)
Openalex Percentile: Top 65%
Appendicitis Diagnosis and Management
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PERSONALIZED APPROACH TO THE PROGNOSIS AND PREVENTION OF INTRA-ABDOMINAL ADHESIONS AFTER APPENDECTOMY — M. B. Uzdenov, Peter Lavreshin, et al. · Bulletin of Pirogov National Medical & Surgical Center (2025) | TGRS Research Map | TGRS