Supplementary Tables S1-S16 from Mutagenic Impact and Evolutionary Influence of Chemoradiotherapy in Hematologic Malignancies
<p>Table S1: Demographic Data. Table S2: Exposure History LBCL. Table S3: Exposure History Myeloma. Tables S4: Exposure History for t-MN from PMID: 36626250. Table S5: ID83 Mutational Signatures Contribution for the Patient-Level Lymphoid Cohort. Table S6: Mutational Signatures Contribution for the Patient-Level Lymphoid Cohort. Table S6: Mutational Signatures Contribution for the Patient-Level Lymphoid Cohort. Table S8: ID8 is independent of genomic complexity in MM. p-values reflect wilcoxcon test of ID8 positive cases stratified by genomic. Table S9: Characteristics of single-cell-derived colonies. Table S10: Viability of DHL-4 cells post treatment (in 10^3 cells). Table S11: De novo mutional signatures extraction for single-cell-derived colonies. Table S12: De novo signature contributions for each colony. Table S13: Signal to Noise Ratios for ChemoRT-Exposed Single Cell-Derived Colonies. Table S14: De-noised mutational and indel signatures fitting of single-cell-derived colonies. Table S15: ID signature fitting to indel profiles of an induced pluripotent stem cell line (Kucab and colleagues, 2019) exposed to various mutagenic and non-mutagenic chemotherapies. Table S16: Indel Signature Re-fit for t-MN samples</p>
Authors
- Benjamin T. Diamond (ORCID: https://orcid.org/0000-0002-8638-9365)
- Michael David Jain (ORCID: https://orcid.org/0000-0002-7789-1257)
- Kylee H. Maclachlan (ORCID: https://orcid.org/0000-0001-7873-4854)
- Saad Z. Usmani (ORCID: https://orcid.org/0000-0002-5484-8731)
- Frederick Lundry Locke (ORCID: https://orcid.org/0000-0001-9063-6691)
- Katja Christina Weisel (ORCID: https://orcid.org/0000-0001-9422-6614)
- Nicholas Figura (ORCID: https://orcid.org/0000-0002-6885-3320)
- Alexandra M. Poos
- Faith E. Davies (ORCID: https://orcid.org/0000-0002-3971-2393)
- Dhanvantri Chahar (ORCID: https://orcid.org/0000-0002-7623-7018)
- Bachisio Ziccheddu (ORCID: https://orcid.org/0000-0002-2746-0053)
- Niels Weinhold (ORCID: https://orcid.org/0000-0002-5464-3234)
- Hartmut Goldschmidt (ORCID: https://orcid.org/0000-0003-0961-0035)
- Marios Papadimitriou (ORCID: https://orcid.org/0009-0009-1852-3495)
- Jonathan Harry Schatz (ORCID: https://orcid.org/0000-0003-1842-228X)
- Marcella Kaddoura (ORCID: https://orcid.org/0000-0002-4529-7405)
- Marc S. Raab (ORCID: https://orcid.org/0000-0003-4181-6922)
- Michael Durante (ORCID: https://orcid.org/0000-0003-3137-6847)
- K. Elias (ORCID: https://orcid.org/0000-0002-6226-1252)
- Tomáš Jelı́nek (ORCID: https://orcid.org/0000-0002-5467-9253)
- Ola Landgren (ORCID: https://orcid.org/0000-0001-6485-4839)
- Roland Fenk (ORCID: https://orcid.org/0000-0001-7594-6288)
- Francesco Maura (ORCID: https://orcid.org/0000-0002-5017-1620)
- Gareth J. Morgan (ORCID: https://orcid.org/0000-0002-4271-6360)
Publication Details
- Published
- 2025-09-03
- DOI
- https://doi.org/10.1158/2643-3230.30040899
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00